Estrogen and Progesterone substitution can in my experience, only work when using micronised natural Estradiol and Progesterone.

According to my own observations, attempts to treat with estradiol valerate
or so-called conjugated estrogens show no signs of success.
No positive effects on the male's serum estradiol could be demonstrated.

The ideal value area of the two hormones for therapy is:
 

Estradiol: 30 - 60 pg/ml
Progesterone: 3 - 10 ng/ml

It follows  that the following regimens are available for therapy:

2x one capsule daily with 0,25 mg natural Estradiol

2x one capsule daily with 50 mg natural Progesterone

added:
10 mg  zinc and
0,014 mg copper

***

product-information by:

Uni-Campus Riedberg - FIZ Biotechnologie
Altenhöfer Allee 3
D-60438 Frankfurt am Main
Phone: +49 (0) 69 92  880 - 300
Fax: + 49 (0) 69 92 880 -  333
(Pharmacist Mr. Peter Cornelius)
Email: info@receptura.com